Evidence from studies of nuclear and mitochondrial DNA extracted from Neanderthal fossils and humans points to fascinating hypotheses concerning the types of interbreeding that occurred between these two species. Humans and Neanderthals share a small percentage of nuclear DNA. However, humans and Neanderthals do not possess the same mitochondrial DNA. In mammals, mitochondrial DNA is exclusively maternally inherited. Taking into account an understanding of interspecific hybridity, the available data leads to the hypothesis that only male Neanderthals were able to mate with female humans. If Haldane’s Law applied to the progeny of Neanderthals and humans, then female hybrids would survive, but male hybrids would be absent, rare, or sterile. Interbreeding between male Neanderthals and female humans, as the only possible scenario, accounts for the presence of Neanderthal nuclear DNA, the scarcity of Neanderthal Y-linked genes, and the lack of mitochondrial DNA in modern human populations.
Paul Mason previously wrote about the topic over at Neuroanthroplogy, so I really don't have much more to say on the topic, other than that I'll get around to reading it over the next couple of days. I'm curious to see if the usual suspects in the genetics (Razib Khan), anthropological (Dienekes) and evolutionary (John Hawks) communities offer some food for thought on the topic.
For me, I'm actually more interested in Mason's recent work on degeneracy... But that's for a later post 😉